Programmed Death Receptor-1-directed Antibody Interactions [MoA] class drugs

11 results

  • jemperli - dostarlimab injection

    (Dostarlimab)
    Glaxosmithkline Llc
    Jemperli treats adults with primary advanced or recurrent endometrial cancer (combined with carboplatin/paclitaxel or as monotherapy for dMMR tumors), and dMMR recurrent or advanced solid tumors that progressed on prior treatment with no satisfactory alternative options.
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    Drug Interactions

  • keytruda - pembrolizumab injection, powder, lyophilized, for solution

    (Pembrolizumab)
    Merck Sharp & Dohme Llc
    Keytruda is a PD-1-blocking immunotherapy indicated for numerous cancers including melanoma, non-small cell lung cancer, head and neck cancer, bladder cancer, colorectal cancer, gastric cancer, cervical cancer, renal cell carcinoma, endometrial carcinoma, triple-negative breast cancer, and other solid tumors.
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  • loqtorzi - toripalimab - tpzi injection

    (Toripalimab-Tpzi)
    Coherus Biosciences, Inc.
    Loqtorzi is a PD-1 blocking antibody for adults with nasopharyngeal carcinoma (NPC): first-line with cisplatin and gemcitabine for metastatic or recurrent locally advanced NPC, or as monotherapy for recurrent unresectable or metastatic NPC after platinum-containing chemotherapy.
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  • opdivo - nivolumab injection

    (Nivolumab)
    E.R. Squibb & Sons, L.L.C.
    Opdivo is a PD-1 blocking antibody indicated for multiple cancers including melanoma, non-small cell lung cancer, renal cell carcinoma, Hodgkin lymphoma, head and neck cancer, urothelial carcinoma, colorectal cancer, hepatocellular carcinoma, esophageal cancer, and gastric cancers in adults and select pediatric patients.
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  • opdualag - nivolumab and relatlimab - rmbw injection

    (Nivolumab And Relatlimab-Rmbw)
    E.R. Squibb & Sons, L.L.C.
    Opdualag treats unresectable or metastatic melanoma in adults and pediatric patients 12 years and older.
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  • tecentriq - atezolizumab injection, solution

    (Atezolizumab)
    Genentech, Inc.
    Tecentriq is a PD-L1 blocking antibody for treating several cancers in adults: non-small cell and small cell lung cancer, hepatocellular carcinoma, BRAF V600-positive melanoma, alveolar soft part sarcoma (including pediatric patients age 2+), and muscle invasive bladder cancer.
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