Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Alimta. Always confirm against the full prescribing information.
100 interactions
5-methyltetrahydrofolic acid
The therapeutic efficacy of Pemetrexed can be decreased when used in combination with 5-methyltetrahydrofolic acid.
Level 2 evidence
Abacavir
Abacavir may decrease the excretion rate of Pemetrexed which could result in a higher serum level.
Level 2 evidence
Abatacept
The metabolism of Pemetrexed can be increased when combined with Abatacept.
Level 1 evidence
Aceclofenac
Aceclofenac may decrease the excretion rate of Pemetrexed which could result in a higher serum level.
Level 1 evidence
Acenocoumarol
The metabolism of Acenocoumarol can be decreased when combined with Pemetrexed.
Level 2 evidence
Acetaminophen
Acetaminophen may decrease the excretion rate of Pemetrexed which could result in a higher serum level.
Level 2 evidence
Acetazolamide
The therapeutic efficacy of Pemetrexed can be increased when used in combination with Acetazolamide.
Level 1 evidence
Acetylsalicylic acid
Acetylsalicylic acid may decrease the excretion rate of Pemetrexed which could result in a higher serum level.
Level 1 evidence
Aclidinium
Aclidinium may decrease the excretion rate of Pemetrexed which could result in a higher serum level.
Level 2 evidence
Acrivastine
Acrivastine may decrease the excretion rate of Pemetrexed which could result in a higher serum level.
Level 2 evidence
Acyclovir
Acyclovir may decrease the excretion rate of Pemetrexed which could result in a higher serum level.
Level 1 evidence
Adalimumab
The metabolism of Pemetrexed can be increased when combined with Adalimumab.
Level 1 evidence
Enter your NPI to unlock 25 major interactions for Alimta
Alimta (Pemetrexed Disodium) has 909 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Alimta (Pemetrexed Disodium) has 203 major, 641 moderate, and 65 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Alimta. Always confirm against the full prescribing information.