Donepezil Hydrochloride Drug Interactions: 69 Major
Donepezil Hydrochloride Drug Interactions
Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Donepezil Hydrochloride. Always confirm against the full prescribing information.
100 interactions
Abatacept
The metabolism of Donepezil can be increased when combined with Abatacept.
Level 1 evidence
Abemaciclib
Abemaciclib may decrease the excretion rate of Donepezil which could result in a higher serum level.
Level 2 evidence
Abiraterone
The metabolism of Donepezil can be decreased when combined with Abiraterone.
Level 1 evidence
Acebutolol
Donepezil may increase the bradycardic activities of Acebutolol.
Level 2 evidence
Aceclidine
The risk or severity of adverse effects can be increased when Donepezil is combined with Aceclidine.
Level 1 evidence
Acetazolamide
The risk or severity of CNS depression can be increased when Acetazolamide is combined with Donepezil.
Level 2 evidence
Acetylcholine
The risk or severity of adverse effects can be increased when Donepezil is combined with Acetylcholine.
Level 1 evidence
Aclidinium
The therapeutic efficacy of Aclidinium can be decreased when used in combination with Donepezil.
Level 1 evidence
Acoramidis
The metabolism of Donepezil can be decreased when combined with Acoramidis.
Level 2 evidence
Adagrasib
The metabolism of Donepezil can be decreased when combined with Adagrasib.
Level 2 evidence
Adalimumab
The metabolism of Donepezil can be increased when combined with Adalimumab.
Level 1 evidence
Afatinib
Afatinib may decrease the excretion rate of Donepezil which could result in a higher serum level.
Level 2 evidence
Enter your NPI to unlock 4 major interactions for Donepezil Hydrochloride
Donepezil Hydrochloride has 963 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Donepezil Hydrochloride has 69 major, 497 moderate, and 397 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Donepezil Hydrochloride. Always confirm against the full prescribing information.