Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Doxycycline Hyclate. Always confirm against the full prescribing information.
100 interactions
Acenocoumarol
The risk or severity of bleeding can be increased when Doxycycline is combined with Acenocoumarol.
Level 1 evidence
Almasilate
Almasilate can cause a decrease in the absorption of Doxycycline resulting in a reduced serum concentration and potentially a decrease in efficacy.
Level 1 evidence
Alteplase
The risk or severity of bleeding can be increased when Doxycycline is combined with Alteplase.
Level 1 evidence
Aluminium phosphate
Aluminium phosphate can cause a decrease in the absorption of Doxycycline resulting in a reduced serum concentration and potentially a decrease in efficacy.
Level 1 evidence
Aluminum hydroxide
Aluminum hydroxide can cause a decrease in the absorption of Doxycycline resulting in a reduced serum concentration and potentially a decrease in efficacy.
Level 1 evidence
Amikacin
Doxycycline may decrease the excretion rate of Amikacin which could result in a higher serum level.
Level 2 evidence
Amobarbital
The serum concentration of Doxycycline can be decreased when it is combined with Amobarbital.
Level 2 evidence
Antithrombin Alfa
The risk or severity of bleeding can be increased when Doxycycline is combined with Antithrombin Alfa.
Level 1 evidence
Antithrombin III human
The risk or severity of bleeding can be increased when Doxycycline is combined with Antithrombin III human.
Level 1 evidence
Apixaban
The risk or severity of bleeding can be increased when Doxycycline is combined with Apixaban.
Level 1 evidence
Argatroban
The risk or severity of bleeding can be increased when Doxycycline is combined with Argatroban.
Level 1 evidence
Articaine
The risk or severity of methemoglobinemia can be increased when Doxycycline is combined with Articaine.
Level 1 evidence
Enter your NPI to unlock 7 major interactions for Doxycycline Hyclate
Doxycycline Hyclate has 933 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Doxycycline Hyclate has 23 major, 168 moderate, and 742 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Doxycycline Hyclate. Always confirm against the full prescribing information.