Entacapone Drug Interactions: 24 Major, 265 Moderate
Entacapone Drug Interactions
Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Entacapone. Always confirm against the full prescribing information.
100 interactions
Acetazolamide
The risk or severity of CNS depression can be increased when Entacapone is combined with Acetazolamide.
Level 2 evidence
Alfentanil
The risk or severity of CNS depression can be increased when Entacapone is combined with Alfentanil.
Level 2 evidence
Almotriptan
The risk or severity of CNS depression can be increased when Entacapone is combined with Almotriptan.
Level 2 evidence
Alosetron
The risk or severity of CNS depression can be increased when Entacapone is combined with Alosetron.
Level 2 evidence
Alprazolam
The risk or severity of CNS depression can be increased when Alprazolam is combined with Entacapone.
Level 2 evidence
Amisulpride
The therapeutic efficacy of Entacapone can be decreased when used in combination with Amisulpride.
Level 2 evidence
Amitriptyline
The metabolism of Amitriptyline can be decreased when combined with Entacapone.
Level 1 evidence
Amobarbital
The risk or severity of CNS depression can be increased when Entacapone is combined with Amobarbital.
Level 2 evidence
Apomorphine
The risk or severity of CNS depression can be increased when Entacapone is combined with Apomorphine.
Level 2 evidence
Aripiprazole
The therapeutic efficacy of Entacapone can be decreased when used in combination with Aripiprazole.
Level 2 evidence
Aripiprazole lauroxil
The therapeutic efficacy of Entacapone can be decreased when used in combination with Aripiprazole lauroxil.
Level 2 evidence
Articaine
The risk or severity of CNS depression can be increased when Entacapone is combined with Articaine.
Level 2 evidence
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Entacapone has 732 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Entacapone has 24 major, 265 moderate, and 443 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Entacapone. Always confirm against the full prescribing information.