Eplerenone Drug Interactions: 86 Major, 272 Moderate
Eplerenone Drug Interactions
Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Eplerenone. Always confirm against the full prescribing information.
100 interactions
Abatacept
The metabolism of Eplerenone can be increased when combined with Abatacept.
Level 1 evidence
Aceclofenac
The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Aceclofenac is combined with Eplerenone.
Level 2 evidence
Acetylsalicylic acid
Acetylsalicylic acid may decrease the excretion rate of Eplerenone which could result in a higher serum level.
Level 1 evidence
Adalimumab
The metabolism of Eplerenone can be increased when combined with Adalimumab.
Level 1 evidence
Alfentanil
The therapeutic efficacy of Eplerenone can be decreased when used in combination with Alfentanil.
Level 2 evidence
Amiloride
The risk or severity of hyperkalemia can be increased when Amiloride is combined with Eplerenone.
Level 1 evidence
Amobarbital
Amobarbital may increase the hypotensive activities of Eplerenone.
Level 2 evidence
Anakinra
The metabolism of Eplerenone can be increased when combined with Anakinra.
Level 1 evidence
Antipyrine
The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Antipyrine is combined with Eplerenone.
Level 2 evidence
Apalutamide
The serum concentration of Eplerenone can be decreased when it is combined with Apalutamide.
Level 1 evidence
Apremilast
The metabolism of Eplerenone can be increased when combined with Apremilast.
Level 1 evidence
Aprepitant
The metabolism of Eplerenone can be decreased when combined with Aprepitant.
Level 1 evidence
Enter your NPI to unlock 6 major interactions for Eplerenone
Eplerenone has 1102 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Eplerenone has 86 major, 272 moderate, and 744 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Eplerenone. Always confirm against the full prescribing information.