Guanfacine Drug Interactions: 36 Major, 434 Moderate
Guanfacine Drug Interactions
Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Guanfacine. Always confirm against the full prescribing information.
100 interactions
Aceclofenac
The therapeutic efficacy of Guanfacine can be decreased when used in combination with Aceclofenac.
Level 2 evidence
Acetazolamide
The risk or severity of CNS depression can be increased when Acetazolamide is combined with Guanfacine.
Level 2 evidence
Acetylcholine
The risk or severity of adverse effects can be increased when Guanfacine is combined with Acetylcholine.
Level 2 evidence
Acyclovir
The risk or severity of adverse effects can be increased when Acyclovir is combined with Guanfacine.
Level 2 evidence
Alfentanil
The risk or severity of CNS depression can be increased when Alfentanil is combined with Guanfacine.
Level 2 evidence
Almotriptan
The risk or severity of CNS depression can be increased when Almotriptan is combined with Guanfacine.
Level 2 evidence
Alosetron
The risk or severity of CNS depression can be increased when Alosetron is combined with Guanfacine.
Level 2 evidence
Alprazolam
The risk or severity of CNS depression can be increased when Alprazolam is combined with Guanfacine.
Level 2 evidence
Amantadine
The risk or severity of adverse effects can be increased when Amantadine is combined with Guanfacine.
Level 2 evidence
Amikacin
Guanfacine may decrease the excretion rate of Amikacin which could result in a higher serum level.
Level 2 evidence
Amiodarone
The metabolism of Guanfacine can be decreased when combined with Amiodarone.
Level 1 evidence
Amisulpride
The risk or severity of CNS depression can be increased when Guanfacine is combined with Amisulpride.
Level 2 evidence
Enter your NPI to unlock 7 major interactions for Guanfacine
Guanfacine has 920 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Guanfacine has 36 major, 434 moderate, and 450 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Guanfacine. Always confirm against the full prescribing information.