Methadone Hydrochloride Drug Interactions: 389 Major
Methadone Hydrochloride Drug Interactions
Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Methadone Hydrochloride. Always confirm against the full prescribing information.
100 interactions
Abatacept
The metabolism of Methadone can be increased when combined with Abatacept.
Level 1 evidence
Abiraterone
The metabolism of Methadone can be decreased when combined with Abiraterone.
Level 1 evidence
Abrocitinib
The metabolism of Abrocitinib can be decreased when combined with Methadone.
Level 2 evidence
Acebutolol
The metabolism of Acebutolol can be decreased when combined with Methadone.
Level 2 evidence
Acenocoumarol
The serum concentration of Acenocoumarol can be increased when it is combined with Methadone.
Level 1 evidence
Acetaminophen
The metabolism of Acetaminophen can be decreased when combined with Methadone.
Level 2 evidence
Aclidinium
The risk or severity of adverse effects can be increased when Aclidinium is combined with Methadone.
Level 1 evidence
Acoramidis
The metabolism of Methadone can be decreased when combined with Acoramidis.
Level 2 evidence
Adagrasib
The metabolism of Methadone can be decreased when combined with Adagrasib.
Level 2 evidence
Adalimumab
The metabolism of Methadone can be increased when combined with Adalimumab.
Level 1 evidence
Adenosine
The risk or severity of QTc prolongation can be increased when Methadone is combined with Adenosine.
Level 2 evidence
Aficamten
The metabolism of Aficamten can be decreased when combined with Methadone.
Level 2 evidence
Enter your NPI to unlock 28 major interactions for Methadone Hydrochloride
Methadone Hydrochloride has 1155 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Methadone Hydrochloride has 389 major, 384 moderate, and 382 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Methadone Hydrochloride. Always confirm against the full prescribing information.