Ondansetron Drug Interactions: 124 Major, 494 Moderate
Ondansetron Drug Interactions
Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Ondansetron. Always confirm against the full prescribing information.
100 interactions
Abatacept
The metabolism of Ondansetron can be increased when combined with Abatacept.
Level 1 evidence
Acebutolol
The metabolism of Ondansetron can be decreased when combined with Acebutolol.
Level 2 evidence
Acenocoumarol
The metabolism of Acenocoumarol can be decreased when combined with Ondansetron.
Level 2 evidence
Acetaminophen
The metabolism of Ondansetron can be decreased when combined with Acetaminophen.
Level 2 evidence
Acetazolamide
The risk or severity of CNS depression can be increased when Acetazolamide is combined with Ondansetron.
Level 2 evidence
Acoramidis
The metabolism of Ondansetron can be decreased when combined with Acoramidis.
Level 2 evidence
Acyclovir
The metabolism of Ondansetron can be decreased when combined with Acyclovir.
Level 2 evidence
Adagrasib
The metabolism of Ondansetron can be decreased when combined with Adagrasib.
Level 2 evidence
Adalimumab
The metabolism of Ondansetron can be increased when combined with Adalimumab.
Level 1 evidence
Adenosine
The risk or severity of QTc prolongation can be increased when Adenosine is combined with Ondansetron.
Level 2 evidence
Alfentanil
The risk or severity of CNS depression can be increased when Alfentanil is combined with Ondansetron.
Level 2 evidence
Almotriptan
The risk or severity of CNS depression can be increased when Ondansetron is combined with Almotriptan.
Level 2 evidence
Enter your NPI to unlock 13 major interactions for Ondansetron
Ondansetron has 991 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Ondansetron has 124 major, 494 moderate, and 373 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Ondansetron. Always confirm against the full prescribing information.