Opsynvi (Macitentan And Tadalafil) Drug Interactions
Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Opsynvi. Always confirm against the full prescribing information.
100 interactions
Abacavir
Abacavir may increase the hepatotoxic activities of Macitentan.
Level 2 evidence
Abiraterone
Abiraterone may increase the hepatotoxic activities of Macitentan.
Level 2 evidence
Acarbose
Acarbose may increase the hepatotoxic activities of Macitentan.
Level 2 evidence
Aceclofenac
The therapeutic efficacy of Macitentan can be decreased when used in combination with Aceclofenac.
Level 2 evidence
Aceclofenac
The therapeutic efficacy of Tadalafil can be decreased when used in combination with Aceclofenac.
Level 2 evidence
Acetaminophen
Acetaminophen may increase the hepatotoxic activities of Macitentan.
Level 2 evidence
Acetazolamide
Acetazolamide may increase the hepatotoxic activities of Macitentan.
Level 2 evidence
Acitretin
Acitretin may increase the hepatotoxic activities of Macitentan.
Level 2 evidence
Albendazole
Albendazole may increase the hepatotoxic activities of Macitentan.
Level 2 evidence
Allopurinol
Allopurinol may increase the hepatotoxic activities of Macitentan.
Level 2 evidence
Alprostadil
The risk or severity of hypotension and priapism can be increased when Tadalafil is combined with Alprostadil.
Level 2 evidence
Amikacin
Tadalafil may decrease the excretion rate of Amikacin which could result in a higher serum level.
Level 2 evidence
Amikacin
Macitentan may decrease the excretion rate of Amikacin which could result in a higher serum level.
Level 2 evidence
Enter your NPI to unlock 6 major interactions for Opsynvi
Opsynvi (Macitentan And Tadalafil) has 1924 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Opsynvi (Macitentan And Tadalafil) has 66 major, 427 moderate, and 1431 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Opsynvi. Always confirm against the full prescribing information.