Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Sovaldi. Always confirm against the full prescribing information.
100 interactions
Abemaciclib
Abemaciclib may decrease the excretion rate of Sofosbuvir which could result in a higher serum level.
Level 2 evidence
Abrocitinib
The serum concentration of Sofosbuvir can be increased when it is combined with Abrocitinib.
Level 2 evidence
Adagrasib
The serum concentration of Sofosbuvir can be increased when it is combined with Adagrasib.
Level 2 evidence
Adenovirus type 7 vaccine live
The therapeutic efficacy of Adenovirus type 7 vaccine live can be decreased when used in combination with Sofosbuvir.
Level 2 evidence
Afatinib
Afatinib may decrease the excretion rate of Sofosbuvir which could result in a higher serum level.
Level 2 evidence
Alectinib
Alectinib may decrease the excretion rate of Sofosbuvir which could result in a higher serum level.
Level 2 evidence
Ambrisentan
The serum concentration of Sofosbuvir can be increased when it is combined with Ambrisentan.
Level 2 evidence
Amikacin
Sofosbuvir may decrease the excretion rate of Amikacin which could result in a higher serum level.
Level 2 evidence
Amiodarone
Sofosbuvir may increase the bradycardic activities of Amiodarone.
Level 1 evidence
Anthrax vaccine
The therapeutic efficacy of Anthrax vaccine can be decreased when used in combination with Sofosbuvir.
Level 2 evidence
Apixaban
The serum concentration of Sofosbuvir can be increased when it is combined with Apixaban.
Level 2 evidence
Arsenic trioxide
The serum concentration of Sofosbuvir can be increased when it is combined with Arsenic trioxide.
Level 2 evidence
Enter your NPI to unlock 1 major interaction for Sovaldi
Sovaldi (Sofosbuvir) has 729 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Sovaldi (Sofosbuvir) has 14 major, 268 moderate, and 447 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Sovaldi. Always confirm against the full prescribing information.