Sumatriptan Drug Interactions: 34 Major, 384 Moderate
Sumatriptan Drug Interactions
Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Sumatriptan. Always confirm against the full prescribing information.
100 interactions
Abemaciclib
Abemaciclib may decrease the excretion rate of Sumatriptan which could result in a higher serum level.
Level 2 evidence
Acetazolamide
The risk or severity of CNS depression can be increased when Sumatriptan is combined with Acetazolamide.
Level 2 evidence
Afatinib
Afatinib may decrease the excretion rate of Sumatriptan which could result in a higher serum level.
Level 2 evidence
Alectinib
Alectinib may decrease the excretion rate of Sumatriptan which could result in a higher serum level.
Level 2 evidence
Alfentanil
The risk or severity of CNS depression can be increased when Sumatriptan is combined with Alfentanil.
Level 2 evidence
Almotriptan
The risk or severity of adverse effects can be increased when Sumatriptan is combined with Almotriptan.
Level 2 evidence
Alosetron
The risk or severity of CNS depression can be increased when Sumatriptan is combined with Alosetron.
Level 2 evidence
Alprazolam
The risk or severity of CNS depression can be increased when Alprazolam is combined with Sumatriptan.
Level 2 evidence
Amantadine
The risk or severity of serotonin syndrome can be increased when Sumatriptan is combined with Amantadine.
Level 2 evidence
Amikacin
Sumatriptan may decrease the excretion rate of Amikacin which could result in a higher serum level.
Level 2 evidence
Amisulpride
The risk or severity of adverse effects can be increased when Sumatriptan is combined with Amisulpride.
Level 2 evidence
Amitriptyline
The risk or severity of adverse effects can be increased when Amitriptyline is combined with Sumatriptan.
Level 2 evidence
Enter your NPI to unlock 1 major interaction for Sumatriptan
Sumatriptan has 948 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Sumatriptan has 34 major, 384 moderate, and 530 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Sumatriptan. Always confirm against the full prescribing information.