Tadalafil Drug Interactions: 25 Major, 187 Moderate
Tadalafil Drug Interactions
Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Tadalafil. Always confirm against the full prescribing information.
100 interactions
Aceclofenac
The therapeutic efficacy of Tadalafil can be decreased when used in combination with Aceclofenac.
Level 2 evidence
Alprostadil
The risk or severity of hypotension and priapism can be increased when Tadalafil is combined with Alprostadil.
Level 2 evidence
Amikacin
Tadalafil may decrease the excretion rate of Amikacin which could result in a higher serum level.
Level 2 evidence
Amiodarone
The serum concentration of Tadalafil can be increased when it is combined with Amiodarone.
Level 1 evidence
Amitriptyline
The risk or severity of hypotension and syncope can be increased when Tadalafil is combined with Amitriptyline.
Level 2 evidence
Amoxapine
The risk or severity of hypotension and syncope can be increased when Tadalafil is combined with Amoxapine.
Level 2 evidence
Antipyrine
The therapeutic efficacy of Tadalafil can be decreased when used in combination with Antipyrine.
Level 2 evidence
Apalutamide
The serum concentration of Tadalafil can be decreased when it is combined with Apalutamide.
Level 1 evidence
Aprepitant
The metabolism of Tadalafil can be decreased when combined with Aprepitant.
Level 2 evidence
Aripiprazole
The risk or severity of hypotension can be increased when Aripiprazole is combined with Tadalafil.
Level 1 evidence
Aripiprazole lauroxil
The risk or severity of hypotension can be increased when Aripiprazole lauroxil is combined with Tadalafil.
Level 1 evidence
Asenapine
The risk or severity of hypotension and syncope can be increased when Tadalafil is combined with Asenapine.
Level 2 evidence
Enter your NPI to unlock 4 major interactions for Tadalafil
Tadalafil has 965 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Tadalafil has 25 major, 187 moderate, and 753 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Tadalafil. Always confirm against the full prescribing information.