Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Tryvio. Always confirm against the full prescribing information.
100 interactions
Aceclofenac
The therapeutic efficacy of Aprocitentan can be decreased when used in combination with Aceclofenac.
Level 2 evidence
Adenine
The metabolism of Aprocitentan can be decreased when combined with Adenine.
Level 2 evidence
Amitriptyline
The metabolism of Aprocitentan can be decreased when combined with Amitriptyline.
Level 2 evidence
Antipyrine
The therapeutic efficacy of Aprocitentan can be decreased when used in combination with Antipyrine.
Level 2 evidence
Aripiprazole
The risk or severity of hypotension can be increased when Aripiprazole is combined with Aprocitentan.
Level 1 evidence
Aripiprazole lauroxil
The risk or severity of hypotension can be increased when Aripiprazole lauroxil is combined with Aprocitentan.
Level 1 evidence
Asciminib
The metabolism of Aprocitentan can be decreased when combined with Asciminib.
Level 2 evidence
Atazanavir
The metabolism of Aprocitentan can be decreased when combined with Atazanavir.
Level 2 evidence
Baclofen
The risk or severity of adverse effects can be increased when Baclofen is combined with Aprocitentan.
Level 1 evidence
Balsalazide
The therapeutic efficacy of Aprocitentan can be decreased when used in combination with Balsalazide.
Level 2 evidence
Bendroflumethiazide
The therapeutic efficacy of Aprocitentan can be increased when used in combination with Bendroflumethiazide.
Level 1 evidence
Carbamazepine
The metabolism of Aprocitentan can be increased when combined with Carbamazepine.
Level 2 evidence
Enter your NPI to unlock 1 major interaction for Tryvio
Tryvio (Aprocitentan) has 358 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Tryvio (Aprocitentan) has 2 major, 111 moderate, and 245 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Tryvio. Always confirm against the full prescribing information.