Xalkori Drug Interactions: 307 Major, 434 Moderate
Xalkori (Crizotinib) Drug Interactions
Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Xalkori. Always confirm against the full prescribing information.
100 interactions
Abacavir
Abacavir may increase the hepatotoxic activities of Crizotinib.
Level 2 evidence
Abemaciclib
The metabolism of Abemaciclib can be decreased when combined with Crizotinib.
Level 1 evidence
Abiraterone
Abiraterone may increase the hepatotoxic activities of Crizotinib.
Level 2 evidence
Acalabrutinib
The metabolism of Acalabrutinib can be decreased when combined with Crizotinib.
Level 1 evidence
Acarbose
Acarbose may increase the hepatotoxic activities of Crizotinib.
Level 2 evidence
Acebutolol
Crizotinib may increase the bradycardic activities of Acebutolol.
Level 1 evidence
Acenocoumarol
The metabolism of Acenocoumarol can be decreased when combined with Crizotinib.
Level 1 evidence
Acitretin
Acitretin may increase the hepatotoxic activities of Crizotinib.
Level 2 evidence
Adenosine
The risk or severity of QTc prolongation can be increased when Adenosine is combined with Crizotinib.
Level 2 evidence
Afatinib
The serum concentration of Afatinib can be increased when it is combined with Crizotinib.
Level 2 evidence
Albendazole
The metabolism of Crizotinib can be decreased when combined with Albendazole.
Level 2 evidence
Alectinib
The metabolism of Alectinib can be decreased when combined with Crizotinib.
Level 1 evidence
Enter your NPI to unlock 26 major interactions for Xalkori
Xalkori (Crizotinib) has 985 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Xalkori (Crizotinib) has 307 major, 434 moderate, and 244 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Xalkori. Always confirm against the full prescribing information.