Xarelto Drug Interactions: 129 Major, 385 Moderate
Xarelto (Rivaroxaban) Drug Interactions
Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Xarelto. Always confirm against the full prescribing information.
100 interactions
Abatacept
The metabolism of Rivaroxaban can be increased when combined with Abatacept.
Level 1 evidence
Abemaciclib
Abemaciclib may decrease the excretion rate of Rivaroxaban which could result in a higher serum level.
Level 2 evidence
Abrocitinib
The serum concentration of Rivaroxaban can be increased when it is combined with Abrocitinib.
Level 2 evidence
Aceclofenac
The risk or severity of bleeding and hemorrhage can be increased when Aceclofenac is combined with Rivaroxaban.
Level 1 evidence
Acetylsalicylic acid
Acetylsalicylic acid may increase the anticoagulant activities of Rivaroxaban.
Level 1 evidence
Adalimumab
The metabolism of Rivaroxaban can be increased when combined with Adalimumab.
Level 1 evidence
Afatinib
Afatinib may decrease the excretion rate of Rivaroxaban which could result in a higher serum level.
Level 2 evidence
Alectinib
Alectinib may decrease the excretion rate of Rivaroxaban which could result in a higher serum level.
Level 2 evidence
Ambrisentan
The serum concentration of Ambrisentan can be increased when it is combined with Rivaroxaban.
Level 2 evidence
Amikacin
Rivaroxaban may decrease the excretion rate of Amikacin which could result in a higher serum level.
Level 2 evidence
Aminosalicylic acid
The risk or severity of bleeding can be increased when Aminosalicylic acid is combined with Rivaroxaban.
Level 2 evidence
Anagrelide
Anagrelide may increase the anticoagulant activities of Rivaroxaban.
Level 1 evidence
Enter your NPI to unlock 17 major interactions for Xarelto
Xarelto (Rivaroxaban) has 1140 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Xarelto (Rivaroxaban) has 129 major, 385 moderate, and 626 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Xarelto. Always confirm against the full prescribing information.